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Brufen 400mg 30 tablets

Brufen 400mg 30 tablets


Ibuprofen is an anti-inflammatory nonsteroidal and antirheumatic agent, a propionic acid derivative. It has analgesic, anti-inflammatory and antipyretic activity


Compound: Each tablet contains:

Ibuprofen – 400mg.

Auxiliary components: corn starch, magnesium stearate, hydroxypropyl methyl cellulose, talc.

Properties: Ibuprofen is an anti-inflammatory nonsteroidal and antirheumatic agent, a propionic acid derivative. It has analgesic, anti-inflammatory and antipyretic activity.

Indications: Treatment of rheumatoid arthritis, joint diseases such as capsulitis, bursitis, tendonitis, tenosynovitis, back pain. In soft tissue injuries: sprains and deformities. For the relief of mild to moderate pain such as dysmenorrhea, dental and postoperative pain and symptomatic relief of migraine headaches.

Mode of application: During or after a meal, with plenty of fluids. Brufen tablets should be taken whole. For adults and children over 12 years of age, the recommended dose is 1200 to 1800 mg/day in divided doses. Some patients may be maintained on a dose of 600 to 1200 mg/day. In severe and acute cases, the dosage can be increased until the acute phase is over. The daily dose should not exceed 2400 mg in divided doses.

Contraindications: Hypersensitivity to ibuprofen or any of the excipients. If previously identified hypersensitivity reactions to ibuprofen, aspirin. Patients with a history of gastrointestinal bleeding or perforation associated with previous NSAID therapy. Active or a history of recurrent peptic ulcer, patients with an increased tendency to bleeding, with cardiovascular disease, severe heart, liver and kidney failure. Last trimester of pregnancy.

Precautionary measures: The shortest possible course and at the lowest effective dose required to relieve symptoms is recommended. If systemic use is necessary for more than 10 days, it is necessary to consult a doctor. During long-term treatment, monitoring of peripheral blood and the state of the liver and kidneys is necessary. Due to severe purulent complications, it is recommended to avoid the use of ibuprofen in chickenpox. Ibuprofen affects ovulation, disrupting female reproductive function (reversible after discontinuation of treatment).

Side effects: Not common: hematopoietic disorders (anemia, leukopenia, etc.), nonspecific allergic reactions, bronchial asthma, skin reactions (itching, urticaria, angioedema, Stevens-Johnson syndrome), allergic rhinitis, tachycardia, arterial hypotension, abdominal pain, nausea , heartburn, bloating; diarrhea, flatulence, constipation, vomiting; gastrointestinal bleeding, ulcerative stomatitis, gastritis; exacerbation of colitis, abnormal liver function, hepatitis and jaundice, acute renal failure; cystitis, headache; aseptic meningitis, heart failure, peripheral edema; with prolonged use, the risk of myocardial infarction, stroke, increased blood pressure is increased. Pregnancy and lactation: Increases the risk of miscarriage, as well as heart defects in early pregnancy. It is not recommended to use during pregnancy or use the minimum dose after consulting a doctor. May be excreted in breast milk. Therefore, it is recommended to stop breast-feeding during the use of the drug.

Storage: Store at a temperature not exceeding 30C in a dry, dark place and out of the reach of children.


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