Description

Compound:

Each tablet contains:

Tadalafil 5 mg

Properties:

Tadalafil is a reversible selective inhibitor of specific phosphodiesterase type 5 (PDE5) of cyclic guanosine monophosphate (cGMP). When sexual arousal causes local release of nitric oxide, inhibition of PDE5 by tadalafil leads to increased concentrations of cGMP in the corpus cavernosum of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and the flow of blood to the tissues of the penis, which causes an erection. Tadalafil has no effect in the absence of sexual arousal.

Indications:

• erectile disfunction;
• symptoms of the lower urinary tract in patients with benign prostatic hyperplasia (for a dosage of 5 mg);
• erectile dysfunction in patients with lower urinary tract symptoms due to benign prostatic hyperplasia (for a dosage of 5 mg).

Directions for use and dosage:

The drug is taken orally.

Erectile disfunction:

For patients with frequent sexual activity (more than 2 times a week): the recommended dosage frequency is daily, 1 time/day, 5 mg, at the same time, regardless of meals. The daily dose can be reduced to 2.5 mg (1/2 tablet 5 mg) depending on individual sensitivity.

For patients with infrequent sexual activity (less than 2 times a week), it is recommended to prescribe the drug at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of the drug.

The maximum daily dose of the drug is 20 mg.

BPH or erectile dysfunction/BPH:

The recommended dose of tadalafil when used once a day is 5 mg; the drug should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is determined by the doctor individually.

Contraindications:

– use of drugs containing any organic nitrates;

– the presence of contraindications to sexual activity in patients with diseases of the cardiovascular system.

– vision loss due to non-arterial anterior ischemic optic neuropathy (regardless of the connection with taking PDE5 inhibitors);

– simultaneous use with doxazosin, other PDE5 inhibitors, other treatment options for erectile dysfunction, with guanylate cyclase stimulators, such as riociguat;

– chronic renal failure (creatinine clearance less than 30 ml/min);

– age up to 18 years;

– lactase deficiency, lactose intolerance, glucose-galactose malabsorption;

– hypersensitivity to tadalafil or to any substance included in the drug.

Precautionary measures:

Diagnosis of erectile dysfunction should include identifying the potential underlying cause, appropriate medical examination, and determining treatment options.

Sexual activity has potential risks for patients with cardiovascular disease. Therefore, treatment of erectile dysfunction, incl. Tadalafil should not be used in men with heart disease for which sexual activity is not recommended.

Side effects:

From the nervous system: often – headache; infrequently – dizziness.

From the side of blood vessels: often – “flushes” of blood to the face; infrequently – decreased blood pressure, increased blood pressure.

From the respiratory system: often – nasal congestion.

From the digestive system: often – dyspepsia.

From the musculoskeletal system: often – back pain, myalgia, pain in the extremities.

Storage method:

Store at a temperature not exceeding 30 degrees.