Description

Compound: Each tablet contains:

Sildenafil 100mg

Auxiliary components: ludiflash , mannitol , crospovidone , polyvinyl acetate , povidone , croscarmellose sodium , microcrystalline cellulose , colloidal silicon dioxide , sucralose , indigo carmine .

Properties: Sildenafil is a potent selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5). The implementation of the physiological mechanism of erection is associated with the release of nitric oxide (NO) in the cavernous body during sexual stimulation. This, in turn, leads to an increase in the level of cGMP, subsequent relaxation of the smooth muscle tissue of the cavernous body and an increase in blood flow. Sildenafil does not have a direct relaxing effect on the isolated human corpus cavernosum, but enhances the effect of NO through inhibition of PDE5, which is responsible for the breakdown of cGMP. A prerequisite for the effectiveness of sildenafil is sexual stimulation. Sildenafil restores impaired erectile function under conditions of sexual stimulation by increasing blood flow to the cavernous bodies of the penis.

Indications: Treatment of erectile dysfunction characterized by an inability to achieve or maintain an erection of the penis sufficient for satisfactory intercourse. Sildenafil is only effective with sexual stimulation.

Dosage and administration: The optimal dosage regimen is determined by the doctor. Compliance of the dosage form of a particular drug with indications for use and dosing regimen should be strictly observed. Treatment of erectile dysfunction: taken orally approximately 1 hour before the planned sexual activity. A single dose is 50 mg. Based on efficacy and tolerability, the dose may be increased to 100 mg or reduced to 25 mg. The maximum single dose is 100 mg. The maximum frequency of application is 1 time / day. For elderly patients over the age of 65 years and with concomitant impaired renal or hepatic function, the dose is 25 mg.

Contraindications: Simultaneous reception of nitric oxide donators or nitrates in any form, hypersensitivity to sildenafil.

Precautionary measures: Before you start taking sildenafil for the treatment of erectile dysfunction, you should conduct an examination of the cardiovascular system. Use with caution in patients with a tendency to bleeding, with peptic ulcer of the stomach and duodenum in the acute phase, with hereditary retinitis pigmentosa. Sildenafil is not used in patients under the age of 18 years. Side effects: From the side of the central nervous system: headache, hot flashes, dizziness, insomnia are possible. From the digestive system: dyspepsia, asthenia, diarrhea, abdominal pain, nausea are possible.

Storage method: In a dry cool place at a temperature not exceeding 30 degrees.